ABSTRACT
The current pandemic due to Covid-19 and its consequent social distancing has accelerated the transformation of traditional education towards online education. However, this transformation has been adapted at a technological level, but not pedagogically. This study has aimed to analyze the acquisition of anatomical knowledge of CAFD students using videos and static images of surfing managed through a blog. A total of 106 students from the CAFD degree at the University of Murcia completed this work. In addition, an exam containing five questions on the anatomy applied to surfing was carried out to analyze the effect on learning after viewing the videos/images. After the statistical analysis, a percentage of correct answers of 66.0%, 51.9%, 62.3%, and 63.2% was observed for questions 1, 2, 4 and 5. This methodology, based essentially on an analysis of movement, allows a functional understanding of the anatomy of the locomotor system in the adventure sport of surfing. These results show a practical and novel methodology for the development of online teaching. Furthermore, they reveal the broad scope for improving the teaching of anatomy in CAFD through the combined use of new technologies.
ABSTRACT
Case report Introduction: Toxic epidermal necrolysis (TEN), is an immune-mediated disease characterized by severe mucocutaneous symptoms and is the result of an inflammatory response that leads to keratinocyte necrosis and perivascular lymphocyte infiltration, mostly drug-related. Case report: A 35-year- old male, with a history of recently diagnosed systemic lupus under treatment with prednisone, hydroxychloroquine, mycophenolate and cotrimoxazole forte evolves with persistent proteinuria, it is decided to add losartan, chlorthalidone and atorvastatin. Nevertheless despite immunosuppression, proteinuria and skin involvement persisted, so mycophenolate was suspended and a bolus of cyclophosphamide 1 g was administered. Eight weeks after adjusting treatment, the patient went to the emergency department due to a confluent, pruritic, maculopapular rash with blistering lesions on the trunk, upper limbs, face, and oral mucosa, associated with fever over 38degreeC, that evolved during one week. On admission, the following was confirmed: confluent erythematous macular exanthem associated with multiple flaccid blisters on the chest, upper limbs and neck, Nikolsky's sign (+), keratoconjunctivitis and dryness on the lips. Admission tests included complete blood count with no leukocytosis or eosinophilia, ESR 29 mm/hr, C-RP 19.8 mg/L, no liver profile abnormalities, creatinine 0.8 mg/dl, and urine test with proteinuria 300 mg/dl. Negative infectious study for mycoplasma, herpes 6 virus, cytomegalovirus, Epstein barr virus, hepatitis A, B, C, E and SARS-COV2 virus. Due to severe mucosal skin involvement, TEN/SJS was suspected v/s (TEN)-like Lupus presentation, drugs used prior to admission (chlorthalidone, losartan, atorvastatin) were discontinued, and treatment was started with Hydrocortisone 100 mg every 8 hours IV, Immunoglobulin 2 g/kg daily IV for 4 days, plus skin and mucous membrane care. Patient had a favorable evolution, with resolution of skin and mucosal lesions and no signs of infection. Skin biopsy showed necrotic epidermis, necrotic basal keratinocytes, and sparse lymphocytic inflammatory infiltrate in the papillary dermis, consistent with erythema multiforme/toxic epidermal necrolysis. Conclusion(s): Extensive mucosal involvement is one of the cardinal signs of the presentation of SJS/ETN and given its severity, a high index of suspicion is important with the consequent suspension of suspected drugs and support management for a favorable evolution. In this case the suspected culprit drug was the combination of cyclophosphamide and chlorthalidone, due to reports of increased toxicity of cyclophosphamide in combination with diuretic drugs.
ABSTRACT
The purpose of the study was to evaluate the variation of air quality parameters: PM10, PM2.5, NO2, and O3 in four districts of Lima-Peru (Carabayllo, San Juan de Lurigancho, Villa María del Triunfo, and Jesús María) in the period 2015-2019 and 2020-2021. Likewise, the ozone variability in the Carabayllo district was modelled. Pollutant concentration data were collected from the National Service of Meteorology and Hydrology of Peru (SENAMHI) from the 4 stations located in the aforementioned districts. The data was processed with the IBM SPSS Statistics v.25 software. A statistically significant decrease was observed between the 2015-2019 and 2020-2021 periods in pollutants PM10, PM2.5, and NO2, in the four monitoring stations, mainly because the country entered in a state of emergency (quarantine due to COVID -19). However, an increase in O3 was observed, attributed to the decrease in NOX concentrations. Finally, the gamma generalized linear model represented 87.6% of the ozone variability in the Carabayllo district, showing a good fit for the field data. © 2022 IEEE.